hScrib | Protein LAP4
AS06 155 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human

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GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains
175 kDa
Reactivity
Application examples
Additional information
Background
Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4
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