hScrib | Protein LAP4

Product no: AS06 155

AS06 155  |  Clonality: Polyclonal  |  Host: Rabbit  |  Reactivity: Human

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  • Product Info
  • Immunogen:

    GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains

    Host: Rabbit
    Clonality: Polyclonal
    Purity: Serum
    Format: Lyophilized
    Quantity: 100 l
    Reconstitution: For reconstitution add 100 µl of sterile water
    Storage: Store lyophilized/reconstituted at -20C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
    Tested applications: Western blot (WB)
    Recommended dilution: 1 : 5 000 (WB)
    Expected | apparent MW:

    175 kDa

  • Reactivity
  • Confirmed reactivity: Human
    Predicted reactivity: Human
    Not reactive in: No confirmed exceptions from predicted reactivity are currently known
  • Additional Information
  • Additional information (application): Reactivity showed on dilluted human cell culture extracts
  • Background
  • Background:

    Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK.  The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4

  • Protocols
  • Antibody protocols
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