hScrib | Protein LAP4

Name: hScrib | Protein LAP4
SKU: AS06 155
Price: 394 EUR
Availability: InStock

AS06 155 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human

hScrib | Protein LAP4 in the group Antibodies Human Cell Biology / Other proteins at Agrisera AB (Antibodies for research) (AS06 155)

Product Information

Immunogen

GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains

Host Rabbit

Clonality Polyclonal

Purity Serum

Format Lyophilized

Quantity 100 µl

Reconstitution For reconstitution add 100 µl of sterile water

Storage Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Tested applications Western blot (WB)

Recommended dilution 1 : 5 000 (WB)

Expected | apparent MW

175 kDa

Reactivity

Confirmed reactivity Human

Predicted reactivity Human

Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Additional information

Reactivity showed on dilluted human cell culture extracts

Background

Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4

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immunogen:	GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains
Reconstitution:	For reconstitution add 100 µl of sterile water
Host:	Rabbit
Clonality:	Polyclonal
Purity:	Serum
Format:	Lyophilized
Quantity:	100 µl
storage:	Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
tested applications:	Western blot (WB)
recommended dilution:	1 : 5 000 (WB)
calculated \| apparent molecular mass [kDa]:	175 kDa
Confirmed reactivity:	Human
predicted reactivity:	Human
not reactive in:	No confirmed exceptions from predicted reactivity are currently known
additional information (application):	Reactivity showed on dilluted human cell culture extracts
background:	Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4