hScrib | Protein LAP4
AS06 155 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human
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Product Information
Immunogen
GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains
Host
Rabbit
Clonality
Polyclonal
Purity
Serum
Format
Lyophilized
Quantity
100 ĩl
Reconstitution
For reconstitution add 100 µl of sterile water
Storage
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Tested applications
Western blot (WB)
Recommended dilution
1 : 5 000 (WB)
Expected | apparent MW
175 kDa
Reactivity
Confirmed reactivity
Human
Predicted reactivity
Human
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Application examples
Additional information
Reactivity showed on dilluted human cell culture extracts
Background
Background
Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4
Product citations
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