Abeta (1-42) | Amyloid-beta peptide 1-42

Product no: AS08 329

AS08 329 | Clonality: Polyclonal | Host: Hen | Reactivity: Human

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Delivery:  3-6 business days
  • Product Info
  • Immunogen: synthetic peptide chosen from human Abeta (1-42) protein, Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
    Host: Chicken
    Clonality: Polyclonal
    Purity: Purified,total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
    Format: Liquid
    Quantity: 100 l
    Storage: Store at 4C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
    Tested applications: Dot Blot (Dot), ELISA (ELISA)
    Recommended dilution: 1 : 1000 (Dot), 1 : 500 (ELISA)
    Expected | apparent MW: 4,5 kDa
  • Reactivity
  • Confirmed reactivity: Human
    Predicted reactivity: Bovine, Chicken, Dog, Porcine, Rabbit
    Not reactive in: No confirmed exceptions from predicted reactivity are currently known
  • Application Examples
  • Dot blot application example

    • Membrane: Nitrocellulose
    • Blocking buffer: 5% dry milk in PBS, 0.1% Tween 20
    • Antibody dilution : 1:1000
    • Secondary antibody: anti-chicken (HRP)
    • Detection: Enhanced Chemoluminescence (pico) 30s

  • Additional Information
  • Additional information (application): The antibody can detect Abeta(1-42), but does not react with Abeta(1-28) Abeta(1-20) or Abeta(1-17)
  • Background
  • Background:

    Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067

  • Protocols
  • Antibody protocols
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