Abeta (1-42) | Amyloid-beta peptide 1-42

AS08 329 | Clonality: Polyclonal | Host: Hen | Reactivity: Human

Product Information

Immunogen synthetic peptide chosen from human Abeta (1-42) protein, Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A

Host Chicken

Clonality Polyclonal

Purity Purified,total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.

Format Liquid

Quantity 100 µl

Storage Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Tested applications Dot Blot (Dot), ELISA (ELISA)

Recommended dilution 1 : 1000 (Dot), 1 : 500 (ELISA)

Expected | apparent MW 4,5 kDa

Reactivity

Confirmed reactivity Human

Predicted reactivity Bovine, Chicken, Dog, Porcine, Rabbit

Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Dot blot application example

• Membrane: Nitrocellulose
• Blocking buffer: 5% dry milk in PBS, 0.1% Tween 20
• Antibody dilution : 1:1000
• Secondary antibody: anti-chicken (HRP)
• Detection: Enhanced Chemoluminescence (pico) 30s

Additional information

The antibody can detect Abeta(1-42), but does not react with Abeta(1-28) Abeta(1-20) or Abeta(1-17)

Background

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067

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additional information (application):	The antibody can detect Abeta(1-42), but does not react with Abeta(1-28) Abeta(1-20) or Abeta(1-17)
Picture (footer):	Dot blot application example • Membrane: Nitrocellulose • Blocking buffer: 5% dry milk in PBS, 0.1% Tween 20 • Antibody dilution : 1:1000 • Secondary antibody: anti-chicken (HRP) • Detection: Enhanced Chemoluminescence (pico) 30s
calculated \| apparent molecular mass [kDa]:	4,5 kDa
Clonality:	Polyclonal
Format:	Liquid
Host:	Chicken
immunogen:	synthetic peptide chosen from human Abeta (1-42) protein, Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
Purity:	Purified,total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
Quantity:	100 µl
recommended dilution:	1 : 1000 (Dot), 1 : 500 (ELISA)
storage:	Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
tested applications:	Dot Blot (Dot), ELISA (ELISA)
Confirmed reactivity:	Human
predicted reactivity:	Bovine, Chicken, Dog, Porcine, Rabbit
not reactive in:	No confirmed exceptions from predicted reactivity are currently known
background:	Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067