Abeta (1-42) | Amyloid-beta peptide 1-42
AS08 328 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human

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Product Information
synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
4.5 kDa
Reactivity
Application examples
Dot blot experiment
• Membrane: Nitrocellulose
• Blocking buffer: 5% dry milk in PBS, 0.1% Tween 20
• Antibody dilution: 1:1000
• Secondary antibody: anti-rabbit (HRP)
• Detection: Enhanced Chemoluminescence (pico) 30s
*Abeta (1-42) consists of both monomeric and partly aggregated mtrl.
Additional information
Background
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067
Product citations
Related products: Abeta (1-42) | Amyloid-beta peptide 1-42
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