GDC-H | H protein of glycine decarboxylase complex (GDC)
AS05 074 | Clonality: Polyclonal | Host: Rabbit | Reactivity: A. thaliana,P.hybrida cv. Mitchell, S. oleracea, T. aestivum, V. faba | cellular [compartment marker] of mitochondrial matrix
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purified GDC-H protein from Spinacia oleracea
15 µg of total protein from Arabidopsis thaliana leaf extract has been loaded per lane. Primary antibody has been used in 1: 5000 dilution using chemiluminescent detection.
Courtesy of Dr Olivier Keech, UPSC, Umeå, Sweden
The Glycine decarboxylase complex (GDC) is abundant in mitochondria of C3 leaves and functions in photorespiratory carbon recovery. GDC enzyme can account for up to 50% of matrix protein, and is responsible for the most prominent metabolic activity in the mitochondria of illuminated leaves, photorespiration. GDC is a multienzyme complex composed of four component enzymes, the P-, H-, T-, and L-proteins and is responsible for the conversion of glycine produced in the peroxisome to serine in the mitochondria during photorespiratory cycle. The H-protein plays a key role as a mobile substrate that commutes between the other subunits, allowing its lipoic acid “arm” to visit the active sites of the other three components.
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