ASyM | Mouse anti-human alpha synuclein N-terminal (clone number 4.2)
AS13 2719 | Clonality: monoclonal | Host: Mouse | Reactivity: Human
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synthetic peptide derived from human alpha-synuclein N-terminal Met1-Val15
For short time storage add sodium azide and store at +4°C.
For long time storage store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
This antibody will recognize human SNCA monomers and multimers in Western blot.
This antibody binds weakly to fibrills in IHC.
Cross reactivity of this antibody to synuclein beta was not determined.
This antibody can be used as a capture antibody in ELISA, combined with AS08 358 as a detection antibody.
Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy.