Pectic polysaccharide, homogalacturonan (monoclonal, clone JIM5)
From the laboratory of Paul Knox, Phd, University of Leeds, United Kingdom
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Has no known cross-reactivity with other polymers.
Binds to paritally methyl esterified homogalacturonan and can also bind to un-esterified homogalacturonan.
Homogalacturonan is a pectic polysaccharide of alpha-1,4 linked galacturonic acid residues. Pectin contains a complex set of polysaccharides that can be found in many primary cell walls.
Clausen et al. (2003). Synthetic methyl hexagalacturonate hapten inhibitors of anti-homogalacturonan monoclonal antibodies LM7, JIM5 and JIM7. Carbohydr Res. 003 Aug 12;338(17):1797-800.doi: 10.1016/s0008-6215(03)00272-6.
Knox et al. (1990). Pectin esterification is spatially regulated both within cell walls and between developing tissues of root apices. Planta. 1990 Jul;181(4):512-21.doi: 0.1007/BF00193004.