Antibodies display different stability depending upon in which format they are stored. Antibodies present in serum
Total IgY fraction (IgY antibodies purified by precipitation from egg yolk) | It may be very tempting to add glycerol as a stabilizer for antibodies, however, what should be considered first, is in which format the antibodies are provided. Glycerol should not be added to serum, as it already contain many proteins with stabilizing effect for antibodies. For antibodies provided as total immunoglobulin preparation and antigen purified antibodies, it is advised to test addition of a glycerol to a smaller aliquot followed by checking antibody performance afterward. There is no golden rule of antibody storage which will fit all antibodies. |
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