Gamma-ECS | Gamma glutamylcysteine synthase
AS06 186 | Clonality: Polyclonal | Host: Rabbit | Reactivity: N.tabacum, S. lycopersicum, Z. mays
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Antibodies has been used in immunolocalization on Arabidopsis thaliana.
Gamma-glutamylcysteine synthase (gamma-ECS) (EC 220.127.116.11) catalyses the first step of glutathione (GSH) synthesis, producing gamma-glutamylcysteine (gamma-EC) from L-glutamate and cysteine. In the second step, catalyzed by GSH-S, glycine is added to the C-terminal end of (gamma-EC). GSH is the predominant non-protein thiol in all nearly where it acts as an antioxidant in stress responses and as a mobile pool of reduced sulfur. It is also important in the regulation of plant growth and development.
Sobrino-Plata et al. (2014). Glutathione is a key antioxidant metabolite to cope with mercury and cadmium stress. Plant Soil, DOI 10.1007/s11104-013-2006-4.
Ghanta et al. (2011). Nicotiana tabacum overexpressing γ-ECS exhibits biotic stress tolerance likely through NPR1-dependent salicylic acid-mediated pathway. Planta 233(5):895-910.