Transthyretin 56-61, amyloid specific (mouse monoclonal)
AS16 3113 | clonality: monoclonal | host: mouse | reactivity: human
|Data sheet||Product citations||Protocols||Add review|
YSTTAVVTNPKE The epitope has been mapped to residue 56-61
It has been suggested that that two distinct mechanisms of TTR-amyloidosis exists. The first, most common seen in wild type TTR Amyloidosis, consists of the full length TTR. Whereas the other type of amyloidosis mainly consists of the C-terminal region of the protein and is more common in mutant versions of TTR. Mouse IgG1 Anti-Transthyretin 56-61 (Amyloid Specific) epitope is located at the C-terminal strand of cleaved TTR and is suitable to detect amyloid formation derived from the C-terminal.
Monoclonal IgG1 antibody. Amyloid specific for human Transthyretin. Detects the C-terminal fragment 49-127 frequently formed in vivo.
Related products: Transthyretin 56-61, amyloid specific (mouse monoclonal)
This product can b...