Toc159 | Chloroplast outer envelope membrane translocon complex protein
AS07 239 | Clonality: Polyclonal | Host: Guinea pig | Reactivity: Pisum sativum
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Recombinant Toc159 (C-terminally His-tagged, including the central GTPase domain but lacking the N-terminal acidic domain as well as the C-terminal membrane associating domain) from Pisum sativum Toc159 protein sequence (Q9LKR1)
Dicots, Nicotiana benthamiana, Oryza sativa
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Toc159 is extremely sensitive to proteolytic processing in vivo therefore use of protease inhibitors is of crucial importance.
Toc159 is located in the outer chloroplast membrane and part of of the Toc/TOC (translocon of the outer envelope membrane of chloroplasts) complex. It mediates the GTP-dependent initial stages of preprotein import into chloroplasts. In Arabidopsis thaliana, Toc159 is encoded by a small gene family: atTOC159, atTOC132, atTOC120, and atTOC90. Phylogenetic analysis suggested that at least two distinct Toc159 subtypes, characterized by atToc159 and atToc132/atToc120, exist in plants.
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