Which classes of immunoglobulin G are found in rabbit serum?

In rabbit serum we will find four immunoglobulin isotypes, namely IgA, IgE, IgG and IgM. However, unlike other mammals, rabbits have only one subclass of IgG. Rabbit IgG is the most abundant immunoglobulin, and constitutes about 75% of the total rabbit serum immunoglobulins, with a concentration from 10-20 mg/ml. 

Other species have four IgG isotypes (subclasses).

Mouse: IgG1, IgG2a, IgG2b and IgG3,

Human: IgG1, IgG2, IgG3 and IgG4


IgG1 is the most abundant subclass in mouse and human serum. There is a difference in function of specific IgG subclasses.

Agrisera provides high-titer secondary antibodies to rabbit IgG:

Unconjugated | ALP-conjugated | HRP-conjugated | Biotinylated | Labelled with a fluorescent dye
  IgG molecule scheme

 Technical blog

Technical blog


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