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Epigenetic research antibody promotion


Agrisera Antibodies for epigenetic research

Gene expression is regulated by epigenetic modifications, which occur either on histones (associated with DNA), on chromatin, or directly on DNA. These modifications include:

  • Methylation of DNA (transcriptional silencing)
  • Histone methylation
  • Histone acetylation

The Agrisera anti-Epigenetic research antibodies include antibodies to the following modifications:

  • H3K4me1 and H3K27ac - these modifications mark enhancers, regions of the genome of cell-type specific activation of gene expression
  • H3K4me3 - modification found in the promoters and active genes
  • H3K9me3 - marks constitutively repressed heterochromatin and works together with DNA methylation
  • H3K27me3 - marks regions of the genome, which are transcriptionally inactive
  • H3K36me3 - modification linked to transcriptional elongation and therefore associated with gene expression
  • 5-mC - addition of a methyl group at the 5 position of cytosines is associated with gene silencing
  • 5-hmC - is a DNA modification and results from the enzymatic oxidation of 5-mC by the TET family of cytosine oxygenases. 5-hmC modification at a gene is associated with its expression level

Agrisera's epigenetics antibody collection is offered at a 15% discount until the end of June.

Use discount code: Epigen15

Valid April-June 2021




2021-03-24 @ 08:41:48